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Analytical Biochemistry Research Centre (ABrC)  |  Pusat Penyelidikan Biokimia Analisis

Services

ABrC is an ISO/IEC 17025 accredited laboratory under Laboratory Accreditation Scheme of Malaysia (SAMM). At present, ABrC is offering the following services:

  1. Workplace Safety - Drugs of Abuse
  2. Food Safety
  3. Persistent Organic Pollutant (POP)
  4. NMR Services
  5. Proteomics, Peptidomics and Metabolomics Services - Protein identification, peptide sequence identification and natural product prediction
  6. Biofermentation Facilities
  7. Polysaccharides and Bioactivities Services
 


Workplace Safety - Drugs of Abuse

workplace safety

Drug and alcohol abuse and their effects on employees have become serious concerns in many countries. Individuals are experimenting with an increasing range of psychoactive substances, leading to an escalating number of problems and spiraling costs. The impact on small to medium sized industries, multinationals and society at large has been estimated in the billions of Ringgit in terms of lower productivity, absenteeism, staff turnover, sickness, accidents, disciplinary problems, workplace disputes and insurance claims. A comprehensive company-wide program targeting drug and alcohol abuse in the workplace can be the single most powerful instrument an employer can use to ensure productivity, safeguard the workplace and promote family stability and harmony. The goals and objectives of such an approach must be clearly defined in a policy statement, which carries the written commitments of both the employer and the employee. Key elements in this strategic plan include prevention through awareness and education, early assistance to halt the casual user and rehabilitation of the habitual abuser. The list of drugs analyzed under the Workplace Safety includes:

  1. Alcohol in Blood
  2. Carboxy-THC in Urine
  3. Benzoylecgonine in Urine
  4. Barbiturates in Urine
  5. Morphine and Codeine in Urine
  6. Benzodiazepines in Urine
  7. Amphetamine and Methamphetamine in Urine
  8. Propoxyphene in Urine
  9. Phencyclidine in Urine
  10. Methadone in Urine
  11. Ketamine in Urine
  12. Ecstasy (MDMA, MDA & MDEA) in Urine
  13. Amphetamine/Methamphetamine Isomer in Urine
  14. Mitragynine in Urine
  15. Hydromorphone and Hydrocodone in Urine
  16. 6-Acetylmorphine in Urine
  17. Oxycodones (Oxymorphone and Oxycodone) in Urine

Food Testing

Food safety

Food is not safe if it would be likely to cause physical harm to a person who might later consume it. However, food is not unsafe, merely because its inherent nutritional or chemical properties cause, or its inherent causes, adverse reactions only in persons with allergies or sensitivities that are not common to the majority. It could be due to the processes during the preparation. This service is offered to private and government agencies in order to inspect food materials for the purpose of safeguarding public health by providing consumers food that is safe, unadulterated and honestly presented. The range of service is as below:

  1. Aristolochic Acid in Herbal Materials
  2. Steroids and Stilbenes in Feed
  3. Polyaromatic Hydrocarbon (PAH) in Fish
  4. Growth Promoter in Feed
  5. 3-Monochloropropandiol-1,2-diol (3-MCPD) in Soy Sauce, Seasoning Powder, Caramel, Maltodextrin and Glucose
  6. Glucocorticosteroids in Powder, Pills and Liquid
  7. Steroids in Fish
  8. Stilbenes in Fish
  9. Aflatoxins in Rice
  10. Authenticity and Traceability using EA-IRMS

 


Persistent Organic Pollutant (POP) Testing

environmental

Environmental pollution is a problem in both developed and developing countries due to population growth and urbanization, which happened since the onset of the industrial revolution. This technology progress has facilitated the production of pollutants. The area of service is defined as the investigation of the chemicals in the environment, such as heavy metal, dioxins, and polychlorobiphenyls (PCBs), which could bring toxic effects to human being. This service will assist private or government agencies to understand the potential effects from hazardous environmental exposures to the public health. The analyses which are provided by ABrC are:

  1. Polychlorinated dibenzodioxins (PCDDs) and Polychlorinated dibenzofurans (PCDFs) in Oil, Fish and Feed
  2. Polychlorinated dibenzodioxins (PCDDs), Polychlorinated dibenzofurans (PCDFs) and Polychlorobiphenyls (PCBs) in Oil, Fish and Feed

 


Advance your research with NMR 700 MHz ASCEND™ spectrometer

IMG 3165

UPNMR At a Glance

IPharm in collaboration with USM under the management of ‘Unit Perkhidmatan NMR’ (UPNMR) provide access to a state-of-the-art NMR facility with Bruker’s 700 MHz  ASCEND™ spectrometer. The facility is ideal for natural products elucidation, structural biology research and materials research applications. Additionally, it comes with a TCI cryo-probe which gives a much needed sensitivity to observe sample amounts that were considered too small only a few years ago.

UPNMR provides

  1. Natural Products and Synthesis Products Platform : Experiment: 1H, 13C, HMBC, HSQC, COSY, TOCSY, NOESY, Full Set Package
  2. Metabolomics and Proteomics Platform : Experiment: 1H, Jres (Profilling), HSQC (profiling), Full Set Package
  3. Time slot (hourly rate) Platform
  4. Unlimited sample (monthly rate) Platform

Note:

  • Price charges may vary with sample turnaround time
  • Price charges depend on the number of samples received
  • Unlimited sample package only for 1H and 13C experiments.

Why Us?

  • Higher sensitivity
  • Better stability and reproducibility
  • Suitable for volume limited samples
  • Quick turnaround time
  • Offers better accuracy and precision required for metabonomics and metabolomics application
  • Platform-based service charge – flexible and affordable rate  

Contact us via email at nmr700mhz@usm.my or abrc_customerservice@usm.my or call us at 04-6536828 for further information.


Proteomics, Peptidomics and Metabolomics Services

Orbitrap          QTOF

  1. Peptide Sequencing
  2. Bioactive Peptide Identification
  3. General Liquid Chromatography Mass Spectrometry Analysis
  4. Protein Profiling using Electrophoresis
  5. Protein/Peptide Profiling using LC-MS/MS
  6. Glycoproteomic Profiling using LC-MS/MS
  7. Label-free Quantitative Proteomics via LC-MS/MS
  8. Metabolite Profiling via LC-MS/MS
  9. Targeted Metabolite Identification and Quantification via LC-MS/MS
  10. Protein/Peptide Quantitative Assay via Spectrophotometry

Contacts:

  1. Assoc. Prof. Dr. Gan Chee Yuen (Peptidomics and Proteomics) - Email: cygan@usm.my
  2. Assoc. Prof. Dr. Mohd Nazri Ismail (Glycoproteomics, Proteomics, glycomics and i2D-PAGE) - Email: mdnazri@usm.my
  3. Customer Service - Email: abrc_customerservice@usm.my

 


 1000084366

 

No.

Instrument

Quantity

Brand

 
 
 

1

Microcentrifuge 2.0mL

2

Eppendorf, 5425G

 

2

Refrigerated Microcentrifuge

1

Eppendorf, 5424R G

 

3

Refrigerated High Speed Centrifuge 50mL

1

Beckman Coulter, Allgera X30R

 

4

High Speed Centrifuge

1

Thermo Scientific, Sorvall Lynx 4000

 

5

Refrigerated Centrifuge

1

Thermo Scientific, Sorvall Legend X1R

 

6

Gel Documentation System

1

Biorad

 

7

Rotiseserie Hybridization Oven

1

Major Science

 

8

UV Transilluminator

2

Benchmark

 

9

DNA Electrophoresis System

2

Thermo Fisher Scientific

 

2

Biorad

 

10

Protein Electrophoresis

3

Thermo Fisher Scientific

 

11

Western Blot System

2

Thermo Fisher Scientific

 

12

Gradient Thermal Cycler (PCR Machine with Gardient Option)

2

Agilent Surecycler 8800

 

13

Gradient Thermal Cycler (PCR Machine with Gardient Option)

1

Applied Biosystem, Verti Pro

 

14

DNA and Protein Quantification System

1

Thermo Scientific

 

15

Real Time (RT) PCR Machine

1

Biorad CFX96

 

16

Real Time (RT) PCR Machine

1

Roche LightCycler 480

 

17

2D Electrophoresis System

1

Biorad

 

18

Autoclave 110 L

3

Hirayama

 

19

Shaking Incubator

1

Esco

 

20

Incubator Shaker with Cooling

1

Infors Multitron

 

21

Orbital Shaker

1

Infors Obitron

 

2

Biosan

 

22

Rocking Shaker

2

Benchmark Scientific

 

23

UV Visible Spectrometer

1

Thermo Genesys 150

 

24

Continuous Centrifuge

1

Alfa Laval Clara 20

 

25

100L S/Steel Automatic Sterilization Bioreactor

1

Infors

 

26

500L S/Steel Automatic Sterilization Bioreactor

1

Infors

 

27

Drum Dryer

1

Buflovak

 

28

Freeze Dryer

1

Labconco, FreeZone Console 12L,-50°C

 

29

Evaporator

1

Eyla, N-1300V-WB

 

30

Autoclave 150L

1

Systec 150L

 

31

Phase Contrast Microscope

1

Olympus (CX43 Set)

 

32

Light Microscope

1

Optika (B-383PLI)

 

 


Polysaccharides Service

  1. Sugar Composition using HPLC

 

Bioactivities Services

  1. α-Amylase Inhibition Activity (Anti-Diabetic Assay)
  2. α-Glucosidase Inhibition Activity (Anti-Diabetic Assay)
  3. Lipase Inhibition Activity (Anti-Obesity Assay)
  4. Monophenolase Inhibition Activity (Anti-Hyper Pigmentation Assay)
  5. Diphenolase Inhibition Activity (Anti-Hyper Pigmentation Assay)
  6. FRAP Anti-Oxidant Assay
  7. DPPH Anti-Oxidant Assay
  8. ABTS Anti-Oxidant Assay

 

Contacts:

  1. Dr. Muhammad Hakimin Shafie - Email: hakiminshafie@usm.my
  2. Customer Service - Email: abrc_customerservice@usm.my
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